About Alexey Nesvizhskii


Associate Professor
Department of Pathology
Department of Computational Medicine & Bioinformatics
University of Michigan, Ann Arbor, Michigan

Full CV: PDF version. Updated January 2014

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Dr. Alexey Nesvizhskii always loved science, and was fortunate to study in Saint Petersburg Lyceum 239 - a special high school with a focus on mathematics and physics considered to be one of the best schools in Russia. He then received his M.S. degree (with honors) in 1995 from the St. Petersburg State Technical University, where he studied in the Department of Physics and Technology - the base academic department of the famed A.F. Ioffe Physico-Technical Institute of the Russian Academy of Sciences. He then continued his studies at the University of Washington in Seattle, USA. While still working on his degree in the area of theoretical solid state physics, he became fascinated with an emerging field of computational biology. Thus, he also attended all core courses in the Department of Molecular Biotechnology (now Genome Sciences), including a course on proteomics taught by Prof. Ruedi Aebersold. After graduation with a Ph.D. degree in Physics in 2001, he decided to make a career switch and joined the Institute for Systems Biology in Seattle - the newly established, pioneering research institute co-founded by the University of Washington scientists Alan Aderem, Ruedi Aebersold, and Leroy Hood. In 2005, Dr. Nesvizhskii joined the Faculty at the University of Michigan in Ann Arbor, where he is now a tenured Associate Professor in the Departments of Pathology and Computational Medicine & Bioinformatics.

Dr. Nesvizhskii's research laboratory is working in the area of bioinformatics, proteomics, and systems biology. The computational tools previously developed by Dr. Nesvizhskii and his colleagues, such as the Trans-Proteomic Pipeline, PeptideAtlas, SAINT, Qspec, and the CRAPome, are used by hundreds of laboratories worldwide. His lab actively collaborates with technology developers, biologists, and clinical scientists on a variety of projects, including analysis protein interaction networks, integrative modeling of multi-omics data to reconstruct targetable pathways in cancer, transcriptomics, metabolomics, and biomarker discovery. Dr. Nesvizhskii has published over 100 manuscripts in international scientific journals. In 2007, he was named a "Rising Young Investigator" by Genome Technology magazine (USA). Dr. Nesvizhskii serves as Senior Editor in the area of bioinformatics and biostatistics for international journals Proteomics and Proteomics-Clinical Applications, as Section Editor in the area of proteomics for BMC Bioinformatics, and on the Editorial Boards of Molecular and Cellular Proteomics. Dr. Nesvizhskii also serves on the Scientific Advisory Board for Swiss Institute of Bioinformatics and on the Board of Directors for the US Human Proteome Organization.

As an enthusiastic educator, Dr. Nesvizhskii directs the NIH funded T32 Proteome Informatics of Cancer Training Program at the University of Michigan, and teaches graduate-level courses in the area of bioinformatics, proteomics, and systems biology. In addition, he has developed and taught several internationally recognized hands-on workshops and tutorials, including a five day Proteome Informatics course at the Institute for Systems Biology in Seattle. His educational efforts have been recognized by several awards, including the Basic Sciences Teaching Award in 2010 and the induction in the League of Educational Excellence at the University of Michigan Medical School in 2013.

  • Post-Doctoral Training
    Institute for Systems Biology, Seattle
  • Physics, Ph.D.
    University of Washington, Seattle
  • Physics/Engineering
    St. Petersburg State Technical University, Russia

Positions and Employment
  • 2011-present
    Associate Professor, Department of Computational Medicine & Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan
  • 2011-present
    Associate Professor, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan
  • 2011-Present
    Director, T32 Advanced Proteome Informatics for Cancer Training Program, University of Michigan, Ann Arbor
  • 2010-2011
    Associate Director, T32 Proteome Informatics for Cancer Training Program, University of Michigan, Ann Arbor
  • 2007-2011
    Assistant Professor, Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan
  • 2005-2011
    Assistant Professor, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan
  • 2003-2005
    Research Scientist, Institute for Systems Biology, Seattle, Washington

  • 2012 Inaugural Member of the League of Educational Excellence, University of Michigan Medical School, Ann Arbor
  • 2010 Basic Sciences Teaching Award, University of Michigan, Ann Arbor
  • 2007 "Rising Young Investigator", Genome Technology magazine
  • 1994-1996 Soros Fellow
  • 1995 Russian Presidential Fellowship
  • 1994 Medal "Best student scientific work", by the Russian State Committee of Higher Education
  • 1994 A.F. Ioffe Physico-Technical Institute Institute Prize

Selected Professional Activities
  • 2013-Present
    Member, Board of Directors, US Human Proteome Initiative (US HUPO)
  • 2011-Present
    Member of the Scientific Advisory Board at Swiss Institute of Bioinformatics
  • 2011-Present
    Section Editor in Proteomics, BMC Bioinformatics
  • 2009-Present
    Senior Editor, Proteomics and its sister journal Proteomics-Clinical Applications (WILEY-VCH)
  • 2009-Present
    Member, Editorial Board, Molecular and Cellular Proteomics
  • 2008-2011
    Section Editor, Journal Amino Acids (Springer)
  • 2011 Co-Chair of the Program Committee
    RECOMB Satellite Conference on Computational Proteomics.
  • 2007-Present
    Member, Organizing Committee, Critical Assessment of Mass Spectrometry-based Protein Identification (CAMSI) Initiative
  • 2004
    Member, Working Group on Publication Guidelines for Peptide and Protein Identification Data, Journal Molecular and Cellular Proteomics
  • 2004
    Member, Organizing Committee, Peptide Fragmentation and Identification Workshop, National Institute of Standards Technology, Maryland
  • 2003-Present
    Grant Reviewer: NIH Special Emphasis Review Panels NIAID "Bioinformatics Resource Centers for Category A-C pathogens and Emerging/Re-Emerging Infectious Disease" and NIDCR, "Molecular Anatomy of Head and Neck Cancer: A Genomic/Proteomic approach", Genome Canada Technology Development Competition Review Panel, National Science Foundation, NIH National Center for Research Resources, National Sciences and Engineering Research Council of Canada, Dutch Cancer Society
  • 2000-Present
    Journal Referee (select list): BMC Genomics, BMC Bioinformatics, Bioinformatics, Proteomics, Molecular and Cellular Proteomics, Journal of Proteome Research, Journal of Mass Spectrometry, Trends Guide to Proteomics, Analytical Chemistry, Expert Reviews in Proteomics, Drug Discovery Today, Nature Biotechnology, Nature Methods, Science

  • More than 100 peer-reviewed publications. Recent publications in Pubmed are here.