Proteome Bioinformatics Lab
Our research interests are in the fields of bioinformatics, proteomics and systems biology, with a focus on the development of computational methods for processing and extracting biological information from complex biological datasets. The efforts in his lab include the development of computational tools and statistical methods for mass spectrometry-based proteomics, establishment of guidelines and standards for proteomic data analysis and publication, computational analysis of protein-protein interaction networks and protein complexes, data mining and machine learning, creation of informatics infrastructure, databases, and proteomic data repositories, biomarker discovery and reconstruction of pathways deregulated in cancer, integration of proteomics with genomics, metabolomics, and other types of biological data. Our lab actively collaborates with technology developers, biologists, and clinical scientists.
- Comprehensive review on Proteogenomics in Nature Methods
- Utility of RNA-seq and GPMDB for improving protein identification in J Prot Research
- SAINTexpress software for AP-MS data in J Proteomics
- On reconstruction of cancer pathways using omics data integration in Nature Commun.
- CRAPome is published in Nature Methods
- iProphet method and software is published in Molecular & Cellular Proteomics
- Special issue of the journal Proteomics on Protein Complexes and Interaction Networks
- New manuscripts on joint analysis of proteomic and RNA-seq transcriptomic data